This chart compares average (solid bars) editing efficiencies and their standard deviation (black lines) between 3 replicates of IVT vs. different formats of synthetic gRNA on a challenging genomic target in HEK293T cells. Industry partner validated data.
I was injecting crustacean embryos within one hour of receiving the RNA from Synthego. Meanwhile, my lab mate still had a long night of PCR, IVT and RNA purification ahead of him.
Our cutting edge research on hemoglobinopathies and immune deficiency diseases at the Children’s hospital requires reagents that have the highest stability, efficiency and consistency.