High Efficiency Chemically Modified
Synthetic sgRNA for CRISPR

Essential for Primary, Stem Cells and Therapeutic Applications

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CRISPR 101 eBook
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CRISPR 101 eBook

Successful Experiments eBook
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Successful CRISPR Experiments eBook

Synthetic sgRNA Poster
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Synthetic sgRNA Poster

CRISPRevolution Synthetic RNA Advantage

Up to 90% Editing Efficiency

CRISPRevolution optimized guide RNA enables gene editing and gene knockout of up to 90% efficiency in cells.

4X Faster Transfection Readiness

Transfection readiness time reduced from weeks down to days. Up to 4X faster compared to plasmid.

Up to 5X Lower Cost Solution

Compared to alternatives from leading competitors, CRISPRevolution is up to 5X lower in cost.

Synthetic sgRNA for World-Class Genome Engineering

Highest Efficiency

No Annealing

Full Length 100-mer

High Throughput

Highest Quality

Modified Options

CRISPRevolution Editing Efficiency vs. IVT

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This chart compares average (solid bars) editing efficiencies and their standard deviation (black lines) between 3 replicates of IVT vs. different formats of synthetic gRNA on a challenging genomic target in HEK293T cells. Industry partner validated data.

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Trusted by Scientists

Synthego is collaborating with many of the top life sciences universities to conduct CRISPR research in applications such as human stem cells, adherent cell lines and mouse embryos.

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walter-eliza
stanford-customer
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I was injecting crustacean embryos within one hour of receiving the RNA from Synthego. Meanwhile, my lab mate still had a long night of PCR, IVT and RNA purification ahead of him.

Erin J., PhD Candidate University of California, Berkeley
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Our cutting edge research on hemoglobinopathies and immune deficiency diseases at the Children’s hospital requires reagents that have the highest stability, efficiency and consistency.

Michelle C., Postdoctoral Fellow SEATTLE CHILDREN’S RESEARCH INSTITUTE
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Have a Question? We’d Love to Hear from You.

For general or partner inquiries give us a call at 888-611-6883 or send us a message

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