CRISPRevolution Synthetic Guide RNA for CRISPR

STARTING AT $79

CRISPRevolution is a portfolio of synthetic RNA designed for CRISPR genome editing and research. Designed by you and built by Synthego, our products offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

EZ RNA Kits

Designed for simple, consistent CRISPR gene edits with a fast turnaround and low cost. Available in crRNA:tracrRNA or sgRNA formats.

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Custom RNA

Custom RNA is tailored to your research – Cpf1, C2c2, S. aureus Cas9 or other novel nuclease. You specify the target sequence and we’ll build it and ship to you direct.

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sgRNA

Achieve the highest editing efficiencies. sgRNA is a full length (100-mer) synthetic guide RNA that requires no annealing and is ready for transfection.

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Modified RNA

RNA is synthesized to contain 2′-O-methyl analogs and 3′ phosphorothioate internucleotide linkages at the first three terminal residues on both 5′ and 3′ ends.

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Libraries

Predesigned screening libraries make CRISPR screening accessible to all researchers with industry-leading, up-front pricing.

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Add-Ons

We offer add-ons for your experiments including Cas9 (300 or 1,000 pmol), annealing and TE buffers and nuclease-free water.

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CRISPRevolution EZ Workflow

Gene knockout using a CRISPRevolution EZ RNA Kit with Cas9 Gene Editing Nuclease Protein is simple:

A CRISPR design tool (for example, MIT CRISPR Designer) is used to create a target sequence within a region of interest in the genome. This target sequence is then used to order a CRISPRevolution EZ RNA Kit.

Genomic editing with Cas9 gene editing nuclease protein and CRISPRevolution EZ Kit guide RNA is performed by co-transfecting all components with a transfection reagent.

One may then observe phenotypes directly, or undertake a genetic screen to estimate gene editing efficiency prior to clonal cell line generation and characterization.

sgRNA - CRISPR workflow resized
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Have a Question? We’d Love to Hear from You.

For general inquiries or questions, give us a call at 888-611-6883 or send us a message

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