Note: The standard modifications described above are not suited for use with Cpf1-based gRNA. Please contact us if you are interested in specialty modifications that are currently being evaluated for use with Cpf1.
Synthego’s chemically modified sgRNA provides a critical tool for our CRISPR research when it comes to difficult stem cell gene targets. Our research into stem cell-based human therapeutics presents editing challenges that require the highest efficiency guides.
[Synthego’s] product allows us to quickly evaluate, in a cost-effective manner, the best guide RNA to stimulate genome editing, including by homologous recombination, in therapeutically relevant human stem cells and primary human T-cells. I highly recommend them.
Additional quantities are available
Optimized for S. pyogenes Cas9
Plate orders only include RNA; Cas9 and buffers can be added on the Order page.