Thinking of using CRISPR but not quite sure where to start or how to get the best results?
CRISPR has revolutionized the field of genome editing, providing a high level of efficiency and precision when targeting the genomes of a vast array of cell types and organisms. The applications around CRISPR are widespread; spanning drug discovery, agriculture, gene therapy and beyond.
Struggling to keep up with the latest news from the world of CRISPR? We’ve got you covered – here’s a whistle-stopped tour of the internet for scientists and researchers who want to keep up to date with what’s happening in the industry. This week’s theme: the future of food; keep on reading to find out how what you’re munching on might change over the coming years, and it’s all down to CRISPR technology.
Synthego’s CRISPRevolution synthetic RNA kits are now being used by scientists throughout the world to achieve unparalleled CRISPR genome editing with minimal time and labor at a fantastic price point. We decided to find out what researchers thought about using our synthetic sgRNA kits, so we caught up with local scientists Erin Jarvis and Heather Bruce from the Patel Lab at University of California, Berkeley to find out more about their experiences.
Image Credit: The Shubin Lab
Children are taught that through the process of evolution, ancient fish left the water and took their first steps on land, ultimately resulting in the development of arms and legs. Biology has one fundamental problem: understanding how the fins of fish evolved into the limbs of tetrapods, the first four-limbed vertebrates and their descendants. A new study published in Nature out of the lab of Neil Shubin at the University of Chicago, Digits and fin rays share common developmental histories (Nakamura et al., 2016), goes some way to answering that question.
Food allergies affect an estimated 15 million Americans, and that figure may be rising; a study released by the Centers for Disease Control and Prevention in 2013 found an increase in food allergies among children of approximately 50% between 1997 and 2011. Eight foods account for about 90% of all reactions: milk, eggs, peanuts, tree nuts, soy, wheat, fish and shellfish, and even trace amounts of allergens can cause life-threatening reactions. There are experimental treatments but still no cure for food allergies, sufferers are told to ensure they strictly avoid allergens, and early recognition and management of allergic reactions are important measures to prevent serious health consequences.
The Rio 2016 Olympic Games are in full swing, but the threat of Zika virus is still very real. We’re now seeing cases spread throughout the state of Florida and the threat is growing. It’s time to focus on improving the way we deal with virus, and CRISPR technology may provide us with the power to prevent the spread of Zika altogether.
Last week we told you about Bloomberg’s video on CRISPR – the video began with a very special mosquito and talk of malaria, but Bloomberg were quick to highlight that mosquitos are not the only target for CRISPR therapeutics, saying that one day the gene editing technology could be used to reverse human aging. We promised we’d revisit that topic on the blog this week, and here we are! Is CRISPR really the solution to all of our anti-wrinkle, collagen boosted dreams?
Last month media giant Bloomberg caught our attention; they published a video online discussing the capabilities and future possibilities for CRISPR. Sometimes scientific concepts can be tricky to convey in a journalistic style so at first we weren’t too hopeful for the contents of the video, but the more we watched, the more impressed we were. Take a look at the video for yourself here, and read on to find out what impressed us so much.
In the world of genome modification, CRISPR is King. It trumped the clumsy characteristics of its predecessors TALENs and zinc-finger nucleases, and provided a simple – yet powerful – method for us to precisely target and edit the genome. A new genome editing technique using DNA as a guide instead of the RNA-guide utilized by CRISPR now threatens the reign of CRISPR, and scientists in the field of genetics and genomics are excited. The new system is based on a protein from the Archaea prokaryote Natronobacterium gregoryi called “Argonaute” (also known as NgAgo), and some have claimed it offers more flexibility and a higher sensitivity to off-target effects; but are we getting ahead of ourselves? Read on to find out what we think the future may hold for CRISPR and NgAgo, and which method we think may end up on top.