CRISPRevolution Synthetic Guide RNA for CRISPR

STARTING AT $99

CRISPRevolution is a portfolio of synthetic RNA designed for CRISPR genome editing and research. Designed by you and built by Synthego, our products offer economical access to fully synthetic RNA for high fidelity editing and increased precision in genome editing.

sgRNA Kits

Designed for consistent CRISPR gene edits, our synthetic single guide RNA (100-mer) requires no annealing and arrives ready for transfection.

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cr:tracrRNA Kits

Designed for researchers exploring CRISPR for the first time, the cr:tracrRNA Kit enables gene edits with a fast turnaround and low cost.

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Custom RNA

Custom RNA is tailored to your research – Cpf1, C2c2, S. aureus Cas9 or other novel nuclease. You specify the target sequence and we’ll build it and ship to you direct.

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Modified RNA

RNA is synthesized to contain 2′-O-methyl analogs and 3′ phosphorothioate internucleotide linkages at the first three terminal residues on both 5′ and 3′ ends.

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CRISPR Design Tool

Easily design and validate CRISPR guides for gene knockout. Choose from over 100,000 genomes and 9,000 species, and design in minutes.

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Add-Ons

We offer add-ons for your experiments including Cas9 (300 or 1,000 pmol), annealing and TE buffers and nuclease-free water.

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CRISPRevolution Workflow

Gene knockout using CRISPRevolution Synthetic RNA Kits with Cas9 nuclease protein is simple:

A CRISPR design tool is used to create a target sequence within a region of interest in the genome. This target sequence is then used to order CRISPRevolution synthetic RNA.

Genomic editing with CRISPRevolution Synthetic RNA Kits and Cas9 nuclease protein is performed by co-transfecting all components with a transfection reagent.

One may then observe phenotypes directly, or undertake a genetic screen to estimate gene editing efficiency prior to clonal cell line generation and characterization.

sgRNA - CRISPR workflow resized
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Have a Question? We’d Love to Hear from You.

For general inquiries or questions, give us a call at 888-611-6883 or send us a message

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