Custom RNA

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Custom RNA is tailored to how you want to do your research: Cpf1, C2c2, S. aureus Cas9 or any novel nuclease. Or to alter the secondary structure of your tracrRNA.

Custom RNA

Tell us the sequence you want and we’ll make you the highest quality RNA – Synthego’s Custom RNA is a fully custom target sequence guide RNA product for genome editing.

Custom RNA 50

Custom RNA 50 is perfect for designing short guide RNAs for nucleases that don’t require long sequences, such as Cpf1. You can use it to design your own Cas9 crRNA and custom 3′ linker to a tracrRNA.

Custom RNA 75

Custom RNA 75 is perfect for designing guide RNAs for nucleases that don’t require guides as long as S. pyogenes Cas9. You can use it to design your own Cas9 tracrRNA and custom 5′ linker to a crRNA.

Custom RNA 100

Custom RNA 100 is perfect for designing full length sgRNA (100-mer) for CRISPR at a practical scale and price point. You can custom design your entire sgRNA sequence from 76-100 nucleotides.

Custom RNA Specifications

Product Type: Fully Synthetic RNA for CRISPR or other applications
Purification: High-Quality Liquid Chromatography SPE
Analysis Method: Electrospray Ionization Mass Spectrometry
Shipping Format: Nuclease-free Tubes

Working with Stem Cells or Other Difficult Targets? Try Chemically Modified Synthetic RNA.

Chemically modified sequences can provide additional RNA stability with improvements in editing efficiency for particular cell types (e.g. stem cells, K562, prokaryotic) and genomic targets that prove otherwise challenging to edit. Please visit our Chemically Modified RNA page for more information.

For a chemically modified version of our synthetic RNA, we offer 2’-O-methyl analogs and 3’ phosphorothioate internucleotide linkages at the first three 5’ and 3’ terminal RNA residues. If you’re interested in a chemically modified option, select “Yes” to “Modified” from the dropdown menu when placing your order. Any questions, please contact us.

Custom RNA Pricing

Contact Us for Special Academic and Volume Pricing

Custom RNA 100

$429

  • Your 76-100nt Sequence
  • Material for 10-20 Transfections
  • Quantity: 3 nmol by OD260
  • Modified RNA Optional*
  • Ships in 5-10 Business Days
Custom RNA 75

$199

  • Your 51-75nt Sequence
  • Material for 25-50 Transfections
  • Quantity: 5 nmol by OD260
  • Modified RNA Optional*
  • Ships in 5-10 Business Days
Custom RNA 50

$119

  • Your 10-50nt Sequence
  • Material for 25-50 Transfections
  • Quantity: 5 nmol by OD260
  • Modified RNA Optional*
  • Ships in 5-10 Business Days

* Chemically modified options ship in 7-10 business days.
Plate orders only include RNA; Cas9 and buffers can be added on the Order page.

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Have a Question? We’d Love to Hear from You.

For general inquiries or questions, give us a call at 888-611-6883 or send us a message

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