mRNA format

This User Guide covers important guidelines for storage, preparation, and getting started with our hfCas12Max nuclease mRNA and gRNA.

hfCas12Max is Synthego's engineered high-fidelity Cas12 variant. It offers high on-target and low off-target editing across various cell types. Delivered in mRNA format, hfCas12Max enables transient nuclease expression, while supporting scalable, flexible CRISPR workflows. Validated across multiple cell types, hfCas12Max nuclease mRNA and gRNA provide a powerful solution for advancing next-generation genome editing strategies.

This User Guide provides step-by-step support for working with hfCas12Max nuclease mRNA and guide RNA (gRNA), including:

  • Storage recommendations for hfCas12Max nuclease mRNA and gRNA
  • Instructions for gRNA preparation and handling
  • Recommended gRNA controls for hfCas12Max nuclease mRNA
  • Key tips for efficient delivery and transfection
  • Guidance on evaluating and interpreting editing outcomes

Download the hfCas12Max nuclease mRNA and gRNA User Guide to accelerate your next therapeutic innovation.