There are multiple design tools available to help simplify the process of CRISPR guide RNA selection and allow you to get on with your experiments. We’ve profiled 4 of the top CRISPR design tools, and given our thoughts on each. Read on to find out what the benefits of each of these tools are, and to find out which may be most suited to your needs.
CRISPR/Cas9 technology relies on two critical components; the Cas9 endonuclease protein that cuts DNA, and the guide RNA (gRNA) that directs Cas9 to its target sequence. The gRNA includes a sequence of 17-20 nucleotides that is unique and tailored to the locus of interest.
The best podcasts covering CRISPR that we could find. From beginners to seasoned researchers, there’s a podcast for everyone. With a multitude of guests and viewpoints, this list contains everything you need to know about CRISPR technology.
The rapid pace of innovation in the CRISPR field can often make it difficult to discern which new developments are in fact improvements to the state of the art. An excellent criterion for judging improvements in the field asks the question: does a tool holistically improve quality and ease-of-use across the board, without any significant drawbacks?
As the Holiday season begins, the streets fill with busy shoppers and scientists remain loyal to their lab benches around the world in an effort to get their experiments finished up in time for the holidays.