The precision of genome editing gives it the potential to develop an entirely new class of therapies for human disease. The headlines around genome editing make it sound simple but the reality is that bringing laboratory discoveries to humans is a complex process requiring specialized expertise, reagents, and commitment.
The guide RNA Cas9 complex worked well for us. We had ordered 3 different guides, and all of them gave a great Knockdown for a highly expressed protein on a suspension NK cell line.
We always get significantly higher editing efficiencies with Synthego's sgRNAs compared to in vitro transcribed sgRNAs.
Synthego's synthetic sgRNA will accelerate our ability to use CRISPR as a gene editing teaching tool by reducing the amount of lab time required while increasing the overall quality of experiments.
It was easy and works great. It's also time-saving!
Synthego sgRNAs cut down months of screening for knockouts and made my life much easier.
Fast turnaround, great packaging and an MS trace of the synthesized RNA made for a pleasant experience!