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eSpOT-ON nuclease is an engineered high-fidelity Cas9 protein designed for therapeutic applications. It offers high on-target editing efficiency while minimizing off-target activity, making it a safer choice for precise cell…
eSpOT-ON is an engineered high-fidelity Cas9 variant, designed for therapeutic gene editing. Delivered in mRNA format, eSpOT-ON provides superior on-target activity with low off-target effects. This nuclease has been validated…
Proofreading hot‑start polymerase delivering higher fidelity than Taq with robust amplification of mid‑length targets. Produces blunt‑end products for cloning and is well‑suited for NGS library amplification. 50x higher fidelity than…
T4 RNA Ligase II ligates 3′‑OH RNA to 5′‑phosphorylated oligos in a duplex context, suppressing adapter‑dimers and artifacts. It enables cleaner small RNA library preparation and supports dsRNA nick sealing…
In IVT, accumulating pyrophosphate (PPi) inhibits T7 and other RNA polymerases. Inorganic pyrophosphatase hydrolyzes PPi to phosphate, preventing product inhibition and sustaining transcription for higher, cleaner mRNA yields at standard…
Integrates reverse transcription with real-time RPA for rapid RNA target quantification. 2× lyophilized master mix supports easy workflow integration with standard instruments. Real‑time detection via exo probes at 37–42 °C…