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From the Bench

CLINICAL CRISPR SOLUTIONS

Dissecting the FDA’s Plausible Mechanism Pathway

The FDA's new "plausible mechanism pathway," born from a groundbreaking bespoke CRISPR therapy case, signals a paradigm shift for complex biologics and personalized medicine. While this framework aims to streamline...
CLINICAL CRISPR SOLUTIONS

Step Inside Synthego: What is a GMP Open House?

Choosing a GMP manufacturing partner is one of the most critical decisions in your clinical development journey. That’s why we created our GMP Open House—a unique opportunity to visit our...
CLINICAL CRISPR SOLUTIONS

AccuBase: An In-Depth Exploration of Cas-Embedded Base Editors

Base editors have promised safer CRISPR therapies, but their clinical translation has faltered owing to their off-target activity. Now, Synthego has partnered with Kactus Biosciences to commercialize AccuBase™ , an...