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eSpOT-ON nuclease is an engineered high-fidelity Cas9 protein designed for therapeutic applications. It offers high on-target editing efficiency while minimizing off-target activity, making it a safer choice for precise cell…
eSpOT-ON is an engineered high-fidelity Cas9 variant, designed for therapeutic gene editing. Delivered in mRNA format, eSpOT-ON provides superior on-target activity with low off-target effects. This nuclease has been validated…
hfCas12Max is a high-fidelity CRISPR nuclease engineered for therapeutic genome editing. It offers high on-target and low off-target editing across various cell types. Its small size and broad PAM sequence…
AccuBase™ is an engineered cytosine base editor designed for therapeutic applications. It enables precise single-base conversions from C to T, minimizing off-target activity and eliminating the risk of double-strand breaks.…
SpCas9 nuclease is a high-quality, recombinant protein that enables robust and reliable genome editing. This widely used CRISPR nuclease, complexed with a synthetic single guide RNA (sgRNA), can achieve high…
Proofreading hot‑start polymerase delivering higher fidelity than Taq with robust amplification of mid‑length targets. Produces blunt‑end products for cloning and is well‑suited for NGS library amplification. 50x higher fidelity than…
T4 RNA Ligase II ligates 3′‑OH RNA to 5′‑phosphorylated oligos in a duplex context, suppressing adapter‑dimers and artifacts. It enables cleaner small RNA library preparation and supports dsRNA nick sealing…
In IVT, accumulating pyrophosphate (PPi) inhibits T7 and other RNA polymerases. Inorganic pyrophosphatase hydrolyzes PPi to phosphate, preventing product inhibition and sustaining transcription for higher, cleaner mRNA yields at standard…
Integrates reverse transcription with real-time RPA for rapid RNA target quantification. 2× lyophilized master mix supports easy workflow integration with standard instruments. Real‑time detection via exo probes at 37–42 °C…
Integrates reverse transcription with endpoint RPA for fast RNA detection at low constant temperatures. Lyophilized 2× mix simplifies setup for gel or lateral‑flow analysis in ~10–20 minutes. RT integrated for…
Monoclonal antibody reversibly inhibits Taq at ambient temperature and releases during initial denaturation. Reduces primer‑dimers and mis‑priming for cleaner, more specific amplification setups. Thermolabile block enables hot‑start PCR Reduces primer‑dimers…